I’m going to refer you to this very informative thread about that very topic. I’ll caution you ahead of time, this thread is gigantic, so I would suggest just cruising through it and picking up a general sense of what it’s about…
https://forum.choiceofgames.com/t/trans-discussion-in-and-out-of-choice-games/21305
Also, try this one…
Hope this clears things up a bit…