I agree with a lot of what has been said here. Certainly a game differentiated according to gender could be done badly, but I believe handled well it could be really interesting.
I think that we’re getting hung up on the idea of sexuality and seduction when there are a ton of other aspects that we could focus on. Giving players the option to push back against gender roles (regardless of their chosen gender) is really attractive to me. I’m really excited to see what @Fawkes does with her game.
On the other hand, there’s nothing wrong with creating a universe in which the MC’s gender doesn’t affect gameplay. Part of the appeal of storytelling is the opportunity to escape reality.