Kinda late to join the discussion, but why not?
I’d be leery of gender-locked games because… why are they gender-locked? Gender-specific plots are not my cup of tea. Someone said a game about a pregnant woman trying to hide her pregnancy had to be gender-locked, but why in the world would i want to play a game with that plot?
So, i tend to think as gender-locked games as less no matter the locked gender. (Male or female, my own gender or not changes nothing) I will assume that the game will either have a boring plot or that the author isn’t good enough to write a non-locked story (which an average writer can).
A great plot can change that. Personally, i loved Magium and that was gender-locked, but that’s basically the only gender-locked game i’ve liked up to now.
As for gender and romance, i do not mind if there’s romance or not because the plot is my main interest, but i truly detest when a certain gender changes much of the story. Yes, i know different genders have physical differences and i am okay with that because that’s the reality. Change the physical description based on gender. That’s completely normal.
What i dislike is when non-physical things change. Many, many games make you the dominant one if male and submissive if female. That, i hate with great passion. Base my dominance/submissiveness on some stats/personality traits or give me the option to choose it instead of basing it entirely on gender.
Or when your roles completely change depending on gender. Some people even attempt to write two games in one, depending on the gender. Like, for example, this one game i played where if you were a male you were a prince and if you were female you were a commoner.
Games that change too much based on gender are a strong no on my part. A bad-rating, not-buying, not-playing-ever-again no.
Supernatural creatures are too human-ish while animals not so much. I’d buy a supernatural creature game like i’d buy any other game…maybe a lot more in case of vampires (i am a sucker for vampires in any setting, though i prefer the horror one). As for aliens, it really depends…
As for the animal one, i could still buy it if i liked it, but i do not usually like animal movies/books so i do not know if i’d be able to like it. (I do not like The Lion King. Blasphemy, i know )
I would buy a game whith a set protagonist as i would buy any other game. I do not self-insert, therefore i am never the protagonist so it wouldn’t make much of a difference to me. Plus i’d love to see what the author had in mind for that particular story. (cough Fallen hero cough i wouldn’t have it any other way)
This are my own opinions and preferences.